Our team members were able to mimic cell rolling by using a microfluidic system and characterize molecules move within elongated protrusions to help stabilize migrating cells inside the bloodstream. “The tethering and rolling step of homing had previously been described as a simple binding between selectins on the endothelium and their ligands on stem cells. Our findings demonstrated that the initial step of homing is far more dynamic and complicated." says Ph.D. student Bader Al Alwan.

Congratulation Bader for this great achievement. Bader’s research focused on the characterization of cell migration and adhesion at the single molecule level. He is currently an assistant professor at Mohammed Al Mana College for Medical Sciences in Dammam, Saudi Arabia.

https://www.nature.com/articles/s42003-021-02398-2

https://discovery.kaust.edu.sa/en/article/1162/the-complex-dynamics-of-stem-cell-tethers-and-slings